Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3

Medicare Coverage Database article A56065

Article

Contractor: Palmetto GBA
States (A/B MAC): AL, GA, NC, SC, TN, VA, WV
Effective: Oct 1, 2026
Contractor numbers: 10112, 10212, 10312, 11202, 11302, 11402, 11502
Official article: A56065 on cms.gov (version 25)

Read the article's coding instructions on CMS — which codes go together, documentation, and frequency limits — before billing. CodeRx lists the codes, not the instructions.

Drug codes in this article

HCPCS Level II drug codes the article lists (other codes it lists are not shown).

Covered ICD-10-CM codes (20)

Diagnosis codes the article lists as supporting medical necessity, grouped as in the article, with CMS's descriptions.

Group 1 · 1 code

D68.2Hereditary deficiency of other clotting factors

Group 2 · 9 codes

D66Hereditary factor VIII deficiency
D68.01Von Willebrand disease, type 1
D68.020Von Willebrand disease, type 2A
D68.021Von Willebrand disease, type 2B
D68.022Von Willebrand disease, type 2M
D68.023Von Willebrand disease, type 2N
D68.03Von Willebrand disease, type 3
D68.04Acquired von Willebrand disease
D68.09Other von Willebrand disease

Group 3 · 5 codes

D66Hereditary factor VIII deficiency
D67Hereditary factor IX deficiency
D68.2Hereditary deficiency of other clotting factors
D68.311Acquired hemophilia
D68.318Other hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors

Group 4 · 1 code

D66Hereditary factor VIII deficiency

Group 5 · 1 code

D67Hereditary factor IX deficiency

Group 6 · 1 code

D68.59Other primary thrombophilia

Group 7 · 2 codes

D66Hereditary factor VIII deficiency
D68.318Other hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors

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