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Billing and Coding: Vitamin B<sub>12</sub> Injections

Medicare Coverage Database article A57755

Article

Contractor
First Coast Service Options, Inc.
States (A/B MAC)
FL, PR, VI
Effective
Apr 1, 2024
Contractor numbers
09102, 09202, 09302
Read the article's coding instructions on CMS — which codes go together, documentation, and frequency limits — before billing. CodeRx lists the codes, not the instructions.

Drug codes in this article

HCPCS Level II drug codes the article lists (other codes it lists are not shown).

Covered ICD-10-CM codes (44)

Diagnosis codes the article lists as supporting medical necessity, grouped as in the article, with CMS's descriptions.

  • D51.0Vitamin B12 deficiency anemia due to intrinsic factor deficiency
  • D51.1Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria
  • D51.2Transcobalamin II deficiency
  • D51.3Other dietary vitamin B12 deficiency anemia
  • D51.8Other vitamin B12 deficiency anemias
  • D51.9Vitamin B12 deficiency anemia, unspecified
  • D52.0Dietary folate deficiency anemia
  • D52.1Drug-induced folate deficiency anemia
  • D52.8Other folate deficiency anemias
  • D52.9Folate deficiency anemia, unspecified
  • D53.1Other megaloblastic anemias, not elsewhere classified
  • D53.9Nutritional anemia, unspecified
  • D81.818Other biotin-dependent carboxylase deficiency
  • D81.819Biotin-dependent carboxylase deficiency, unspecified
  • E40Kwashiorkor
  • E41Nutritional marasmus
  • E42Marasmic kwashiorkor
  • E44.1Mild protein-calorie malnutrition
  • E45Retarded development following protein-calorie malnutrition
  • E46Unspecified protein-calorie malnutrition
  • E53.8Deficiency of other specified B group vitamins
  • E64.0Sequelae of protein-calorie malnutrition
  • G32.0Subacute combined degeneration of spinal cord in diseases classified elsewhere
  • K29.30Chronic superficial gastritis without bleeding
  • K29.40Chronic atrophic gastritis without bleeding
  • K29.50Unspecified chronic gastritis without bleeding
  • K86.0Alcohol-induced chronic pancreatitis
  • K86.1Other chronic pancreatitis
  • K90.0Celiac disease
  • K90.1Tropical sprue
  • K90.2Blind loop syndrome, not elsewhere classified
  • K90.3Pancreatic steatorrhea
  • K90.41Non-celiac gluten sensitivity
  • K90.49Malabsorption due to intolerance, not elsewhere classified
  • K90.821Short bowel syndrome with colon in continuity
  • K90.822Short bowel syndrome without colon in continuity
  • K90.83Intestinal failure
  • K90.89Other intestinal malabsorption
  • K90.9Intestinal malabsorption, unspecified
  • K91.1Postgastric surgery syndromes
  • K91.2Postsurgical malabsorption, not elsewhere classified
  • T50.995A*Adverse effect of other drugs, medicaments and biological substances, initial encounter
  • T50.995D*Adverse effect of other drugs, medicaments and biological substances, subsequent encounter
  • T50.995S*Adverse effect of other drugs, medicaments and biological substances, sequela

* The article sets additional coding requirements for these codes (for example, a second diagnosis). Read them on the CMS article.

Disclaimer. This application provides informational coding and reimbursement reference data. It does not constitute legal, clinical, coding, or billing advice. Codes, payment amounts, payer rules, and coverage policies can change. Verify all information with current CMS publications, the applicable payer, and your organization’s compliance policies before submitting a claim. CodeRx is not affiliated with or endorsed by CMS, FDA, Medicare, or any payer.