Definity Rt

Injection, perflutren lipid microspheres, per ml

Derived: 1 of 2 NDC package(s) for this drug appear in the CMS NDC–HCPCS crosswalk for Q9957. CMS quarters Q2 2022 – Q3 2026Not in the latest CMS crosswalk.

Q-codes are temporary national codes recognized by Medicare. For drugs they include biosimilar products (Q51xx) and other drugs, biologicals, and skin substitutes that are not yet assigned a permanent code. Units follow the dosage in the descriptor.

Home infusion per diem (S-codes)

When a home infusion pharmacy dispenses this drug, the drug is billed with the code above and each day of pharmacy services, supplies, and equipment with a per diem S-code. CMS publishes no drug-to-per-diem crosswalk, so CodeRx picks the therapy category from the FDA pharmacologic class and route. S-codes are not payable by Medicare; confirm the code against the payer contract.

• Not otherwise classified

  Derived calculationVerification needed

  No category matched · FDA class: Contrast Agent for Ultrasound Imaging

  • S9379Infusion therapy with no specific per diem codeFits this drug’s routeCMS: Home infusion therapy, infusion therapy, not otherwise classified
  • S9542Injectable therapy with no specific per diem codeCMS: Home injectable therapy, not otherwise classified

  No specific category was found in this drug’s FDA pharmacologic class. Use a specific code instead when the therapy is one CodeRx cannot detect: hydration (S9373–S9377), tocolytic (S9349), anti-spasmodic (S9363), blood products (S9538), or irrigation (S9590).

Home infusion per diem (S-codes)

Medicare

Not payable by Medicare — CMS coverage code I (all 2 codes)

Part B pricing indicator

00 — Not separately priced by Part B (all 2 codes)

National payment amount

None. No per diem code here is in the CMS Part B payment limit file for Q4 2026; CMS sets no national per diem rate.

Washington Apple Health (Medicaid)

Not on HCA’s Home Infusion Therapy/Parenteral Nutrition Program fee schedule (effective Jul 1, 2026), so these per diems are not separately paid. Home infusion is paid with the supply, pump, and nutrition codes in that schedule instead (below).

Billing unit

1 unit = 1 day on service (the CMS descriptor ends “per diem”)

Who sets the rate

Each commercial plan’s contract or state Medicaid fee schedule. Some payers reduce a second per diem billed for the same day.

Billed separately

The drug, with its own HCPCS code and units, and nursing visits — the CMS descriptor says “drugs and nursing visits coded separately”.

Verification neededCodeRx links to coverage documents instead of copying them: CMS distributes their code lists under AMA, ADA, and AHA license terms that limit reuse. Medicare Advantage, Medicaid, and commercial plans set their own coverage and prior-authorization rules.

Noridian (Jurisdiction F, Washington) has no current Billing and Coding article for these codes.

Every import with its checksum is listed on the data sources page.